龍爾平

個(gè)人簡(jiǎn)歷

2010-2015  中山大學(xué) 臨床醫學(xué)學(xué)士學(xué)位 

2015-2020  中山大學(xué) 臨床醫學(xué)博士學(xué)位

2018-2020  密歇根大學(xué) 博士生聯(lián)合培養 

2021-2023  美國國立衛生研究院NIH 博士后

2023-至今   中國醫學(xué)科學(xué)院基礎醫學(xué)研究所 研究員

主要研究方向

龍爾平課題組主要運用“臨床醫學(xué)-人工智能-基因組學(xué)”多學(xué)科交叉的研究手段，開(kāi)展人類(lèi)疾病的遺傳易感性研究和智慧醫療的轉化應用： 

1. 1.運用單細胞和功能組學(xué)技術(shù)，挖掘復雜性疾病GWAS基因座區域內的功能位點(diǎn)和易感基因；
2. 2.整合基因組學(xué)和群醫學(xué)隊列數據，揭示重大疾病間的共性遺傳基礎和多效性演化規律；
3. 3.基于臨床數字檔案和機器學(xué)習算法，探索大數據驅動(dòng)的重大慢病智慧醫療模式與落地應用。

招聘計劃

課題組計劃在生物信息/群體遺傳、機器學(xué)習/大數據挖掘方向招聘2名助理研究員（事業(yè)編制），將提供個(gè)人職業(yè)生涯的穩定上升空間。

同時(shí)，本課題組長(cháng)期招收碩/博研究生，博士后和研究助理，可提供與NIH等國際前沿課題組交流合作的機會(huì )，充分支持個(gè)人長(cháng)期職業(yè)發(fā)展。

郵箱：erping.long@ibms.pumc.edu.cn

實(shí)驗室英文網(wǎng)站：https://sites.google.com/view/erping-long-lab/

代表性論文

*denotes equal contributor, ^#denotes corresponding author

Long E, Zhang J^#. Evidence for the role of selection for reproductively advantageous alleles in human aging. Science Advances 2023 (Highlighted by The New York Times, ‘Genes That Boost Fertility Also Shorten Our Life, Study Suggests’)

Long E*^#, Wan P*, Chen Q, Lu Z, Choi J^#. From function to translation: decoding genetic susceptibility to human diseases via artificial intelligence. Cell Genomics 2023

Long E*, Yin J*, Funderburk K, …, Choi J^#. Massively parallel reporter assays with variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity. American Journal of Human Genetics 2022 (Highlighted by American Journal of Human Genetics, ‘Paving a post-GWAS pathway’)

Long E,…, Choi J^#. The case for increasing diversity in tissue-based functional genomics datasets to understand human disease susceptibility. Nature Communications 2022

Byun J*, Han Y*, Li Y*, Xia J*, Long E*, Choi J, …, Amos CI^#. Trans-ancestry genome-wide meta-analysis of 60,290 cases and 896,712 controls identifies novel genomic cross-ancestry loci contributing to lung cancer susceptibility. Nature Genetics 2022 (Highlighted by Cancer Discovery, ‘Cross-ancestry Genomic Data Reveal New Susceptibility Loci in Lung Cancer’)

Long E, Zhang J^#. Natural selection contributes to the myopia epidemic. National Science Review 2021

Long E*, Chen J*, Wu X*, Lin Z*, Wang L*, …, Lin H^#. Artificial intelligence manages congenital cataracts with individualized prediction and telehealth computing. NPJ Digital Medicine 2020

Long E, Zhang J^#. The coupon collection behavior in human reproduction. Current Biology 2020 (Highlighted by Nature, ‘Parents desire for one boy and one girl pushed trend in family patterns’; Highlighted by Current Biology, 'The Sex Ratio: A Biological and Statistical Conundrum')

Long E, Zhang J^#. Retesting the influences of mutation accumulation and antagonistic pleiotropy on human senescence and disease. Nature Ecology & Evolution 2019

Long E*, Lin Z*, Xiang Y*,…, Lin H^#, Liu Y^#. Discrimination of the behavioural dynamics of visually impaired infants via deep learning. Nature Biomedical Engineering 2019 (Cover Highlights)

Wan P, Long E^#. Pollution Control for a Healthier Chinese Population. Lancet Planetary Health 2018.

Long E^#. Evolutionary medicine: Why does prevalence of myopia significantly increase? Evolution, Medicine, Public Health 2018

Long E*, Lin H*^#,…, Liu Y^#. An artificial intelligence platform for the multihospital collaborative management of congenital cataracts. Nature Biomedical Engineering 2017 (Cover Highlights)

Wan P, Long E^#. Expectations of medical students in China. Lancet 2016

Lin H, Long E, Chen W, Liu Y^#. Documenting rare disease data in China. Science 2015

學(xué)術(shù)獎勵

2020  吳瑞獎  吳瑞紀念基金會(huì )

2021  Fellows Awards for Research Excellence (FARE), National Institues of Health (NIH), USA

2021  Reviewers’ Choice Award, American Society of Human Genetics (ASHG), USA

2022  Director Innovation Award, National Institues of Health (NIH), USA

2022  Informatics Tool Challenge Award, National Cancer Institute (NCI), USA