劉偉

研究方向：神經(jīng)系統的衰老機制

介紹：劉偉，男，副教授，博士畢業(yè)于北京協(xié)和醫學(xué)院生物化學(xué)與分子生物學(xué)專(zhuān)業(yè)，現在北京協(xié)和醫學(xué)院人體解剖與組織胚胎學(xué)系任教。從事解剖教學(xué)15年，多次在青年教師教學(xué)比賽獲得優(yōu)異成績(jì)。主要研究方向是神經(jīng)系統發(fā)育及神經(jīng)系統退行性疾病，相關(guān)文章發(fā)表在Neurobiology of aging，JBC等雜志。

聯(lián)系方式：liuwei@ibms.cams.cn

代表性論文：

1. Wei Liu# ，Chang Liu#，Jingxi Zhu，Pengcheng Shu，Bin Yin，YanhuaGong，Boqin Qiang，Jiangang Yuan，Xiaozhong Peng*，MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice，Neurobiology of Aging，2012，33（3）：522-534。

2. Liu W，Liu C，Zhu JX，Li AH，Zhao ZQ，Yin B，Peng XZ*，D-Tyr-tRNA~ (Tyr) Deacylase,a New Role in Alzheimer’s-associated Disease in SAMP8 Mice，Chinese Medical Sciences Journal，2010，（02）：90-94。

3. 劉偉,劉暢,陰彬,彭小忠*.衰老相關(guān)miRNAs的篩選和鑒定.基礎醫學(xué)與臨床，2015,35(5):674-679

4. 劉偉,劉暢,陰彬,彭小忠*. miR-9和miR-9*在SAMP8小鼠衰老中的功能及機制.中國醫學(xué)科學(xué)院學(xué)報，2015，37（3）：253-258

5. Xiaoyan Liu#, Zhengguang Guo#, Wei Liu#, Wei Sun*，Chao Ma*. Differential proteome analysis of hippocampus and temporal cortex using label-free based 2D-LC-MS/MS. Journal of Proteomics, 165 ：26-34.

6. Shu P#, Wu C#, Liu W#, Ruan X#, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X. The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar8;294(10):3444-3453.

7. Pengcheng Shu, Chao Wu, Xiangbin Ruan, Wei Liu, Lin Hou, Hongye Fu, Ming Wang, Chang Liu, Yi Zeng, Pan Chen, Bin Yin, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng*, and Weimin Zhong* (2019). Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell 49, 764-785 e764.

8. Liang Li, Xiangbin Ruan, Chang Wen, Pan Chen, Wei Liu, Liyuan Zhu, Pan Xiang, Xiaoling Zhang, Qunfang Wei, Lin Hou, Bin Yin, Jiangang Yuan, Boqin Qiang, Pengcheng Shu*, Xiaozhong Peng* (2019). The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep 28, 698-711 e695.